{"id":1834,"date":"2021-08-17T15:13:58","date_gmt":"2021-08-17T22:13:58","guid":{"rendered":"https:\/\/news.venturacounty.gov\/?p=1834"},"modified":"2022-02-18T15:15:40","modified_gmt":"2022-02-18T23:15:40","slug":"additional-mrna-dose-for-immunocompromised-persons","status":"publish","type":"post","link":"https:\/\/news.venturacounty.gov\/en\/additional-mrna-dose-for-immunocompromised-persons\/","title":{"rendered":"Additional mRNA Dose for Immunocompromised Persons"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1834\" class=\"elementor elementor-1834\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2dfe026 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2dfe026\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3033543\" data-id=\"3033543\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9ef2830 elementor-widget elementor-widget-text-editor\" data-id=\"9ef2830\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: right;\"><strong>Download article:<\/strong> <a href=\"https:\/\/vcportal.ventura.org\/CEO\/VCNC\/press_releases\/2021-08-17_vcph_pr_additional-mrna-dosepfor-immunocompromised-persons.pdf\" target=\"_blank\" title=\"Press Release - English\">English<\/a><\/p>\n<p>This message is intended for all healthcare providers in the County of Ventura.<br \/>Please distribute as appropriate.<\/p>\n<p>Key Messages<\/p>\n<ul>\n<li>The CDC recommends an additional mRNA COVID-19 vaccine dose for moderately and severely immunocompromised people after an initial 2-dose primary mRNA vaccine series.<\/li>\n<li>An additional vaccine dose is not currently recommended by the CDC for immunocompromised persons who received a single dose of the J&#038;J vaccine. The FDA is still evaluating data on the effectiveness of this vaccine for immunocompromised individuals.<\/li>\n<li>Other fully vaccinated persons are adequately protected and do not need an additional dose nor a booster dose of COVID-19 vaccine at this time.<\/li>\n<\/ul>\n<p>View the Clinician Outreach and Communication Webinar Here:<br \/><a href=\"https:\/\/emergency.cdc.gov\/coca\/calls\/2021\/callinfo_081721.asp\" target=\"_blank\">https:\/\/emergency.cdc.gov\/coca\/calls\/2021\/callinfo_081721.asp<\/a><\/p>\n<p><strong>Additional Dose of mRNA Vaccine for Moderate and Severely Immunocompromised Persons.<\/strong><\/p>\n<p>A 2-dose series of Pfizer and Moderna vaccine works very well in the majority of individuals, but there is evidence that some people who are moderately to severely immunocompromised have a reduced immune response and may benefit from a third dose. The CDC\u2019s Advisory Committee on Immunization Practices (ACIP) <a href=\"https:\/\/www.cdc.gov\/media\/releases\/2021\/s0813-additional-mRNA-mrna-dose.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fmedia%2Freleases%2F2021%2Fs0813-additional-mRNA-mrna-dose.html.html\" target=\"_blank\">recommends<\/a> that people who are moderately to severely immunocompromised receive an additional dose of mRNA COVID-19 vaccine at least four weeks after completing their initial series. This ACIP recommendation follows the <a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/coronavirus-covid-19-update-fda-authorizes-additional-vaccine-dose-certain-immunocompromised\" target=\"_blank\">FDA amendment<\/a> to emergency use authorizations (EUAs) for both the Pfizer and Moderna vaccines to allow for the use of an additional vaccine dose for certain immunocompromised.<\/p>\n<p>For public health purposes, the CDC states that immunocompromised persons are still considered fully vaccinated &gt; 2 weeks after completing a primary vaccine series (i.e., 2-dose Pfizer or Moderna vaccine series or a single dose of the Janssen vaccine). However, an additional third dose should be considered for people with moderate to severe immune compromise due to a medical condition or receipt of immunosuppressive medications or treatments. These conditions and treatments include but are not limited to:<\/p>\n<ul>\n<li>Active treatment for solid tumor and hematologic malignancies \u2022 Receipt of solid-organ transplant and taking immunosuppressive therapy<\/li>\n<li>Receipt of CAR-T-cell or hematopoietic stem cell transplant (within 2 years of transplantation or taking immunosuppression therapy)<\/li>\n<li>Moderate or severe primary immunodeficiency (e.g., DiGeorge syndrome, WiskottAldrich syndrome)<\/li>\n<li>Advanced or untreated HIV infection<\/li>\n<li>Active treatment with high-dose corticosteroids (i.e., \u226520mg prednisone or equivalent per day), alkylating agents, antimetabolites, transplant-related immunosuppressive drugs, cancer chemotherapeutic agents classified as severely immunosuppressive, tumor-necrosis (TNF) blockers, and other biologic agents that are immunosuppressive or immunomodulatory.<\/li>\n<\/ul>\n<p><strong>Additional information for providers regarding the level of immune suppression associated with a range of medical conditions and treatments can be found:<\/strong><\/p>\n<ul>\n<li>ACIP: <a href=\"https:\/\/www.cdc.gov\/vaccines\/hcp\/acip-recs\/general-recs\/immunocompetence.html\" target=\"_blank\">General Best Practice Guidelines for Immunization-Altered Immunocompetence<\/a><\/li>\n<li>CDC: <a href=\"https:\/\/wwwnc.cdc.gov\/travel\/yellowbook\/2020\/travelers-with-additional-considerations\/immunocompromised-travelers\" target=\"_blank\">Yellow Book-Immunocompromised Travelers<\/a><\/li>\n<li>IDSA: <a href=\"https:\/\/academic.oup.com\/cid\/article\/58\/3\/e44\/336537\" target=\"_blank\">Clinical Practice Guideline for Vaccination of the Immunocompromised Host<\/a><\/li>\n<\/ul>\n<p>The CDC has updated COVID-19 vaccine <a href=\"https:\/\/www.cdc.gov\/vaccines\/covid-19\/clinical-considerations\/covid-19-vaccines-us.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fvaccines%2Fcovid-19%2Finfo-by-product%2Fclinical-considerations.html\" target=\"_blank\">clinical considerations<\/a> to include a new section on the <a href=\"https:\/\/www.cdc.gov\/vaccines\/covid-19\/clinical-considerations\/covid-19-vaccines-us.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fvaccines%2Fcovid-19%2Finfo-by-product%2Fclinical-considerations.html#considerations-additional-vaccine-dose\" target=\"_blank\">considerations for use of an additional mRNA COVID-19 vaccine dose<\/a> for immunocompromised persons. Some key points include:<\/p>\n<ul>\n<li>The currently FDA-authorized COVID-19 vaccines are not live vaccines and therefore can be safely administered to immunocompromised people.<\/li>\n<li>The additional dose should be administered at least 28 days after the completion of the initial mRNA COVID-19 vaccine series.<\/li>\n<li>Ideally individuals should be vaccinated with the same vaccine as they received during their first and second dose but if that is not possible receiving a third dose with another mRNA vaccine is also acceptable. \u2022 This additional dose recommendation is only for persons who are moderately or severely immunocompromised.<\/li>\n<\/ul>\n<p>The CDC has also published a <a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/recommendations\/immuno.html\" target=\"_blank\">new page<\/a> for consumers COVID-19 Vaccines for Moderately to Severely Immunocompromised People.<\/p>\n<p>Qualified individuals can go to any vaccine site for their third dose. More information at <a href=\"https:\/\/www.venturacountyrecovers.org\/vaccine-information\/\" target=\"_blank\">www.venturacountyrecovers.org\/vaccine-information\/<\/a><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Download article: English This message is intended for all healthcare providers in the County of Ventura.Please distribute as appropriate. Key Messages The CDC recommends an additional mRNA COVID-19 vaccine dose [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":1796,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_mo_disable_npp":"","footnotes":""},"categories":[35,6],"tags":[],"class_list":["post-1834","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hca","category-news"],"_links":{"self":[{"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/posts\/1834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/comments?post=1834"}],"version-history":[{"count":0,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/posts\/1834\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/media\/1796"}],"wp:attachment":[{"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/media?parent=1834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/categories?post=1834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/news.venturacounty.gov\/en\/wp-json\/wp\/v2\/tags?post=1834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}